A nuclear-powered bus embarks on a perilous journey from New York City to Denver, Colorado, plagued by a series of calamities orchestrated by a shadowy group tied to the oil industry. When the original driver is incapacitated, a former bus driver with a checkered past is recruited to steer the behemoth vehicle, featuring an onboard swimming pool and bowling alley.

The Big Bus
A high-tech bus carrying nuclear energy embarks on a treacherous trip from New York City to Colorado, with a clandestine alliance between the oil industry and a malevolent group posing a significant threat to the transport and potentially triggering a devastating chain reaction.