Andrea Kay Pyle, professionally known as Missi Pyle, was born on November 16, 1972, in Houston, Texas. She was raised in Memphis, Tennessee, by her parents, Linda and Frank Pyle, along with her four older siblings, Debbie, Julie, Sam, and Paul.
Pyle attended the North Carolina School of the Arts, graduating in 1995. Following her graduation, she began her acting career, landing a minor role in the comedy film As Good as It Gets (1997) alongside Jack Nicholson and Helen Hunt.
She went on to secure notable roles in various films, including Galaxy Quest (1999),Home Alone 4: Taking Back the House (2002),Big Fish (2003),Charlie and the Chocolate Factory (2005),Just My Luck (2006),and Soccer Mom (2008). Pyle also appeared in numerous television series, such as Mad About You (1992),Frasier (1993),The One with Ross' Teeth (1999),Ally McBeal (1997),Two and a Half Men (2003),Boston Legal (2004),Grey's Anatomy (2005),Heroes (2006),and The Mentalist (2008).
As a voice actress, Pyle has lent her voice to several episodes of Family Guy (1999) and American Dad! (2005). Her notable guest roles on television series include Mad About You (1992),Frasier (1993),The One with Ross' Teeth (1999),Ally McBeal (1997),Two and a Half Men (2003),Boston Legal (2004),Grey's Anatomy (2005),Heroes (2006),and The Mentalist (2008).
Missi Pyle's musical career began when she met Shawnee Smith in 2007 while filming an ABC comedy pilot. The actresses formed the country-rock band Smith & Pyle in Los Angeles, California, and released their debut album "It's OK to Be Happy" (2008) under their own record label.
